反应详情

[see Kodadeck et. al. J. Am. Chem. Soc. (2004), 126(13), 4088-4089.] The crude product (68) was combined with aqueous sodium bicarbonate solution (20 mL, 0.75 N) and stirred for 3 days. The compound was then removed from the aqueous phase using continuous distillation in ether overnight. The organic phase was then evaporated to get a white solid. (0.032 g) 1H NMR (400 MHz, CDCl3): δ 1.36 (s, 12H), 1.84 (s, 4H), 3.41 (b, 2H), 4.00 (s, 4H).

1. customThe compound was then removed from the aqueous phase
2. distillationdistillation in ether overnight
3. customThe organic phase was then evaporated
4. customto get a white solid