(5-Azidomethyl-furan-2-ylmethyl)-carbamic Acid Tert-Butyl Ester → HCID 60035026, compound

HRID 34106Notes

Reaction equation

HRID 34106 reaction equation
[C:1]([O:5][C:6](=[O:18])[NH:7][CH2:8][C:9]1[O:10][C:11]([CH2:14][N:15]=[N+]=[N-])=[CH:12][CH:13]=1)([CH3:4])([CH3:3])[CH3:2]>C(O)C.[Pd].CC([O-])=O.CC([O-])=O.[Pb+2]>[C:1]([O:5][C:6](=[O:18])[NH:7][CH2:8][C:9]1[O:10][C:11]([CH2:14][NH2:15])=[CH:12][CH:13]=1)([CH3:4])([CH3:2])[CH3:3]

Participants

4

Reactant 1

HCID 60053847(5-Azidomethyl-furan-2-ylmethyl)-carbamic Acid Tert-Butyl Ester

Product 1

HCID 60035026HCID 60035026, compoundYield 101.9%

Reagents, catalysts & solvents 2

HCID 131709914Lindlars catalystCatalystHCID 702EthanolSolvent

Procedure

To a solution of 88.6 mg of (5-azidomethyl-furan-2-ylmethyl)-carbamic acid tert-butyl ester in 3 mL of ethanol was added 30 mg of Lindlar catalyst, stirred at room temperature under hydrogen atmosphere for 15 hours, the catalyst filtered off, and the solvent was evaporated, to afford 81 mg of the title compound as a colorless oil.

Workup

  1. filtrationthe catalyst filtered off
  2. customthe solvent was evaporated

Sources & evidence

ORD record
ord-c1cd73bbdc5141dab72dbd3f5b96d8e6
Source dataset
uspto-grants-2008_09
Patent number
US07429609B2

Reaction notes

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