HRID34117

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID2832231

1-Amino-3-(morpholin-4-yl)propan-2-ol

C7H16N2O2

结构：COc1c(C(=O)O)ccc2[nH]nc(/C=C/c3ccc(F)cc3)c12

HCID59797243

未命名化合物

PRODUCTS

生成物

结构：COc1c(C(=O)NCC(O)CN2CCOCC2)ccc2[nH]nc(/C=C/c3ccc(F)cc3)c12

HCID60034861

未命名化合物

收率 45.4%

PROCEDURE

实验过程

100 mg of 3-[(E)-2-(4-fluorophenyl)-vinyl]-4-methoxy-1H-indazole-5-carboxylic acid obtained by Example 234 and 130 mg of 1-amino-3-(morpholine-4-yl)propane-2-ol were condensed in the similar method as described in Example 44, to afford 66 mg of the title compound as colorless needle crystals.

WORKUP

后处理

customcondensed in the similar method