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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 341178Generated: November 1, 2026

Trifluoroacetic acid → HCID 44176786, compound

https://huagongshe.com/reaction/341178

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 59320870HCID 59320870—
SolventDichloromethaneHCID 6344—
ProductHCID 44176786HCID 4417678615.1%

Reaction Steps

Trifluoroacetic acid (1 ml) was added to a stirred solution of [2-(3-{3-[7-(4-fluoro-phenyl)-imidazo[1,2-a]pyridin-3-yl]-phenyl}-ureido)-ethyl]-carbamic acid tert-butyl ester (85 mg, 0.17 mmol) in CH2Cl2 (2 ml) at 0° C. After 1 h the volatiles were removed in vacuo and the residue was purified by preparative HPLC to give the title compound (10 mg, solid).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08895745B2
Source datasetuspto-grants-2014_11
ORD IDord-af1d2184507645128186506e2d11b43e
Source noteuspto-grants-2014_11