Methylamine → HCID 59321028, compound

HRID 341250Notes

Reaction equation

HRID 341250 reaction equation
[CH3:1][C:2]1O[C:5]([C:7]2[CH:12]=[CH:11][N:10]3[C:13]([C:16]4[CH:17]=[C:18]([NH:22][C:23]([NH:25][CH2:26][C:27]([F:30])([F:29])[F:28])=[O:24])[CH:19]=[CH:20][CH:21]=4)=[CH:14][N:15]=[C:9]3[CH:8]=2)=[N:4][N:3]=1.[CH3:31][NH2:32]>>[CH3:31][N:32]1[C:2]([CH3:1])=[N:3][N:4]=[C:5]1[C:7]1[CH:12]=[CH:11][N:10]2[C:13]([C:16]3[CH:17]=[C:18]([NH:22][C:23]([NH:25][CH2:26][C:27]([F:30])([F:29])[F:28])=[O:24])[CH:19]=[CH:20][CH:21]=3)=[CH:14][N:15]=[C:9]2[CH:8]=1

Participants

3

Reactant 2

HCID 6329MethylamineHCID 56589627HCID 56589627, compound

Product 1

HCID 59321028HCID 59321028, compound

Procedure

Alternatively the title compound could be prepared through reaction of 1-{3-[7-(5-methyl-[1,3,4]oxadiazol-2-yl)-imidazo[1,2-a]pyridin-3-yl]-phenyl}-3-(2,2,2-trifluoro-ethyl)-urea with methylamine.

Sources & evidence

ORD record
ord-d462d7d674de45f2bfb92c46147f2191
Source dataset
uspto-grants-2014_11
Patent number
US08895745B2

Reaction notes

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