化工社化工社 化学情報印刷レポート · 研究参考用
Acetic Anhydride → N-(4-Bromo-5-fluoro-2-methylphenyl)acetamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Acetic Anhydride | HCID 7918 | — |
| 反応物 | 4-Bromo-5-fluoro-2-methylaniline | HCID 7018044 | — |
| 生成物 | N-(4-Bromo-5-fluoro-2-methylphenyl)acetamide | HCID 23070217 | — |
反応手順
73.6 mL of acetic anhydride was added with 80.0 g of 4-bromo-5-fluoro-2-methylphenylamine at room temperature, and stirred at this temperature for 10 minutes. Excess acetic anhydride was distilled off under reduced pressure, and the precipitated crystals were washed with water, to afford 77.6 g of the title compound as colorless crystal.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07429609B2 |
| 出典データセット | uspto-grants-2008_09 |
| ORD ID | ord-d239774155d24cce85ad6d774c49788d |
| 出典メモ | uspto-grants-2008_09 |