Sodium Hydroxide → Sodium 3-methoxypyridine-2-carboxylate

Participants

Reaction Steps

To a stirred solution of methyl 3-methoxypyridine-2-carboxylate (Intermediate 95, 0.55 g, 3.3 mmol) in methanol (10 ml) was added dropwise aqueous sodium hydroxide solution (1M, 4 ml, 4 mmol). The mixture was left to stand overnight. The mixture was concentrated under vacuum to give a white solid, which was used without further purification or characterisation.

Provenance & Evidence