Hydrochloric Acid → HCID 10039116, compound

HRID 341776Notes

Reaction equation

Cl.[N:2](C(OC(C)(C)C)=O)([CH3:21])[C@@H:3]([C:11]([N:13]1[CH2:20][CH2:19][CH2:18][C@H:14]1[C:15]([OH:17])=[O:16])=[O:12])[CH2:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1>>[NH:2]([CH3:21])[C@@H:3]([C:11]([N:13]1[CH2:20][CH2:19][CH2:18][C@H:14]1[C:15]([OH:17])=[O:16])=[O:12])[CH2:4][C:5]1[CH:6]=[CH:7][CH:8]=[CH:9][CH:10]=1

Participants

Reactant 2

HCID 313Hydrochloric Acid

HCID 11783729HCID 11783729, compound

Product 1

HCID 10039116HCID 10039116, compound

Procedure

The title compound was synthesized as hydrochloride from Boc-N-Me-D-Phe-ProOH (Bajusz et al., J. Med. Chem. 1990, 33, 1729-1735) and 3-(2-amino-ethyl)-2,5-dihydropyrrole-1-(N,N'-di-tert.-butoxycarbonyl) carboxamidine (example 3 k) by the same method as described in example 31). FAB-MS: m/z 412 MH+.

Sources & evidence

ORD record: ord-29812f3d48144153a14fb12ac9abbaed
Source dataset: uspto-grants-1999_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05856309

Reaction notes

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