HuagongsheHuagongshe Chemistry Print Report · For research reference only
5,6-dihydro-2-(2-phenylethyl)-4H-imidazo[4,5,1-ij]quinolin-6-amine → 5,6-dihydro-2-(2-phenylethyl)-4H-imidazo[4,5,1-ij]quinolin-6-amine hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5,6-dihydro-2-(2-phenylethyl)-4H-imidazo[4,5,1-ij]quinolin-6-amine | HCID 15838467 | — |
| Reactant | Hydrochloride methanol | HCID 21893726 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 5,6-dihydro-2-(2-phenylethyl)-4H-imidazo[4,5,1-ij]quinolin-6-amine hydrochloride | HCID 67598032 | 97.7% |
Reaction Steps
A portion (1.9 g) of 5,6-dihydro-2-(2-phenylethyl)-4H-imidazo[4,5,1-ij]quinolin-6-amine obtained in Step 2 of Example 17 was dissolved in methanol (20 mL) and 10% HCl-methanol solution (3.0 g) was added slowly. The solvent was removed under reduced pressure to yield the titled compound as colorless crystals (2.1 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05856334 |
| Source dataset | uspto-grants-1999_01 |
| ORD ID | ord-a5cb1a3c43f941a38c424e054e58c256 |
| Source note | uspto-grants-1999_01 |