Methanesulfonic Acid → Phosphorus Pentoxide-Methanesulfonic Acid

Participants

Reaction Steps

Eaton's reagent was prepared by adding P2O5 (200 g) in approximately 50 g portions to methanesulfonic acid (2000 mL) at 95° C. under argon with vigorous mechanical stirring. The addition of P2O5 in portions prevented it from forming a hard mass at the bottom of the flask. A clear, very pale brown solution was obtained. Eaton et al. J. Org. Chem., 38, 4071-4073 (1973).

Provenance & Evidence