Methanesulfonic Acid → Phosphorus Pentoxide-Methanesulfonic Acid

HRID 341978Notes

Reaction equation

HRID 341978 reaction equation
[O:1]=[P:2]12[O:13][P:11]3([O:14][P:4]([O:6][P:7]([O:10]3)([O:9]1)=[O:8])(=[O:5])[O:3]2)=[O:12].[CH3:15][S:16]([OH:19])(=[O:18])=[O:17]>>[CH3:15][S:16]([OH:19])(=[O:18])=[O:17].[O:5]=[P:4]12[O:3][P:2]3([O:9][P:7]([O:10][P:11]([O:13]3)([O:14]1)=[O:12])(=[O:8])[O:6]2)=[O:1]

Participants

3

Reactant 2

HCID 6395Methanesulfonic AcidHCID 14812Phosphorus oxide (P4O10)2×

Product 1

HCID 86584057Phosphorus Pentoxide-Methanesulfonic Acid

Procedure

Eaton's reagent was prepared by adding P2O5 (200 g) in approximately 50 g portions to methanesulfonic acid (2000 mL) at 95° C. under argon with vigorous mechanical stirring. The addition of P2O5 in portions prevented it from forming a hard mass at the bottom of the flask. A clear, very pale brown solution was obtained. Eaton et al. J. Org. Chem., 38, 4071-4073 (1973).

Workup

  1. customfrom forming a hard mass at the bottom of the flask
  2. customA clear, very pale brown solution was obtained

Sources & evidence

ORD record
ord-cc2364e337164552b51117712a93e978
Source dataset
uspto-grants-1999_01
Patent number
US05856507

Reaction notes

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