4-Methoxybenzenethiol → HCID 54108474, compound

HRID 342033Notes

Reaction equation

HRID 342033 reaction equation
Br[C:2]1[N:3]=[C:4]([C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)[N:5]([CH2:9][C:10]2[C:18]([Cl:19])=[CH:17][C:13]3[O:14][CH2:15][O:16][C:12]=3[CH:11]=2)[C:6]=1[CH:7]=[O:8].[H-].[Na+].[CH3:28][O:29][C:30]1[CH:35]=[CH:34][C:33]([SH:36])=[CH:32][CH:31]=1>>[Cl:19][C:18]1[C:10]([CH2:9][N:5]2[C:6]([CH:7]=[O:8])=[C:2]([S:36][C:33]3[CH:34]=[CH:35][C:30]([O:29][CH3:28])=[CH:31][CH:32]=3)[N:3]=[C:4]2[C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)=[CH:11][C:12]2[O:16][CH2:15][O:14][C:13]=2[CH:17]=1

Participants

4

Reactant 3

HCID 127654-MethoxybenzenethiolHCID 24758Sodium hydrideHCID 54309636HCID 54309636, compound

Product 1

HCID 54108474HCID 54108474, compound

Procedure

The operation is carried out as in Example 2 starting with 4 g of the product of Example 6 using 640 mg of sodium hydride at 50% in oil and 1.64 ml of 4-methoxy thiophenol and in this way 4.05 g of expected product is obtained. (M.p.=116° C.).

Sources & evidence

ORD record
ord-0ccce7ded03b4746ba4da32caa4132f5
Source dataset
uspto-grants-1999_01
Patent number
US05856509

Reaction notes

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