Hydrochloric Acid → HCID 178499561, compound

HRID 342122Notes

Reaction equation

HRID 342122 reaction equation
[ClH:1].[NH:2]1[CH:6]=[C:5]([CH2:7][C:8]([OH:10])=[O:9])[N:4]=[CH:3]1.Cl.[CH3:12]O>>[ClH:1].[CH3:12][O:9][C:8](=[O:10])[CH2:7][C:5]1[N:4]=[CH:3][NH:2][CH:6]=1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 887MethanolHCID 178479752HCID 178479752, compound

Product 1

HCID 178499561HCID 178499561, compound

Procedure

To a solution of 1H-imidazole-4-acetic acid hydrochloride (4.00 g, 24.6 mmol) in methanol (100 ml) was bubbled hydrogen chloride gas until saturated. This solution was allowed to stand for 18 h at room temperature and the solvent evaporated in vacuo to give the title compound as a white solid. 1H NMR(CDCl3, 400 MHz) δ 8.85(1H, s),7.45(1H, s), 3.89(2H, s) and 3.75(3H, s) ppm.

Workup

  1. customthe solvent evaporated in vacuo

Sources & evidence

ORD record
ord-94bc28d4d97d472ea01ba98efe259a80
Source dataset
uspto-grants-1999_01
Patent number
US05856326

Reaction notes

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