Water → HCID 11102507, compound

Participants

Reaction Steps

A solution of 0.26 g of (RS)-5-[6-(allyl-methyl-amino)-hexyloxy]-2-[1-(4-bromo-phenyl)-1-hydroxy-allyl]-phenol in 50 ml of o-xylene is boiled at 170° C. on a water separator for 2 hrs., evaporated and the residue is purified over silica gel with methylene chloride/methanol 95:5. There is obtained 0.18 g of allyl-[6-[4-(4-bromo-phenyl)-2H-chromen-7-yloxy]-hexyl]-methyl-amine, MS: m/e 456 (M+H+, 1 Br).

Provenance & Evidence