反应详情

A mixture of 3-chloroacetyl-2-methyl-7-nitrobenzo[b]furan (431 mg) and thiourea (194 mg) in ethanol (10 ml) was refluxed for 1.5 hours. The separated solid was collected, washed with ethanol and dried to give 3-(2-aminothiazol-4-yl)-2-methyl-7-nitrobenzo[b]furan hydrochloride (485 mg).

1. temperaturewas refluxed for 1.5 hours
2. customThe separated solid was collected
3. washwashed with ethanol
4. customdried