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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 342443Generated: October 25, 2026

2-Ethyl-3-methyl-7-nitrobenzo[b]furan → (2-Ethyl-3-methyl-1-benzofuran-7-yl)amine

https://huagongshe.com/reaction/342443

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Ethyl-3-methyl-7-nitrobenzo[b]furanHCID 70201232—
CatalystHCID 178418390HCID 178418390—
SolventMethanolHCID 887—
Solvent1,4-DioxaneHCID 31275—
Product(2-Ethyl-3-methyl-1-benzofuran-7-yl)amineHCID 25219482100.5%

Reaction Steps

To a solution of 2-ethyl-3-methyl-7-nitrobenzo[b]furan (1.00 g) in a mixture of methanol (15 ml) and dioxane (10 ml) was added 10% palladium carbon (100 mg) and the above mixture was hydrogenated at 3 atom for 1 hour. The catalyst was filtered off and the filtrate was evaporated in vacuo to give 7-amino-2-ethyl-3-methylbenzo[b]furan (858 mg) as an oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05858995
Source datasetuspto-grants-1999_01
ORD IDord-1ac95174c9a348449c08125b550a52ed
Source noteuspto-grants-1999_01