HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Ethyl-3-methyl-7-nitrobenzo[b]furan → (2-Ethyl-3-methyl-1-benzofuran-7-yl)amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Ethyl-3-methyl-7-nitrobenzo[b]furan | HCID 70201232 | — |
| Catalyst | HCID 178418390 | HCID 178418390 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | (2-Ethyl-3-methyl-1-benzofuran-7-yl)amine | HCID 25219482 | 100.5% |
Reaction Steps
To a solution of 2-ethyl-3-methyl-7-nitrobenzo[b]furan (1.00 g) in a mixture of methanol (15 ml) and dioxane (10 ml) was added 10% palladium carbon (100 mg) and the above mixture was hydrogenated at 3 atom for 1 hour. The catalyst was filtered off and the filtrate was evaporated in vacuo to give 7-amino-2-ethyl-3-methylbenzo[b]furan (858 mg) as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05858995 |
| Source dataset | uspto-grants-1999_01 |
| ORD ID | ord-1ac95174c9a348449c08125b550a52ed |
| Source note | uspto-grants-1999_01 |