NSC251211 → HCID 15308300, compound

Participants

Reaction Steps

A suspension of 4.70 g of 6-(3,4-dimethoxyphenyl)-2,3,4,5-tetrahydropyridazin-3-one ("A") in 150 ml of THF is treated with 2.24 g of potassium tert-butoxide and the mixture is stirred for 30 minutes. 7.32 g of 4-nicotinoylaminobenzyl chloride is added and the mixture is subsequently stirred at room temperature for 10 hours. The solvent is removed and the residue is worked up in the customary manner. 2-(4-nicotinoylaminobenzyl)-6-(3,4-dimethoxyphenyl)-2,3,4,5-tetrahydropyridazin-3-one is obtained.

Provenance & Evidence