HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(4-Chloro-2-methoxyphenyl)piperazine → 3-benzyl-1-{3-[4-(4-chloro-2-methoxyphenyl)piperazin-1-yl]propyl}-5-methyl-2,4(1H,3H)-pyrimidinedione hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(4-Chloro-2-methoxyphenyl)piperazine | HCID 15840663 | — |
| Reactant | 1-(3-chloropropyl)-3-benzyl-5-methyl-2,4(1H,3H)-pyrimidinedione | HCID 15840667 | — |
| Product | 3-benzyl-1-{3-[4-(4-chloro-2-methoxyphenyl)piperazin-1-yl]propyl}-5-methyl-2,4(1H,3H)-pyrimidinedione hydrochloride | HCID 70201269 | — |
Reaction Steps
substituting 1-(4-chloro-2-methoxyphenyl)piperazine and 3-benzyl-1-(3-chloropropyl)-5-methyl-2,4(1H,3H)-pyrimidinedione gave 3-benzyl-1-{3-[4-(4-chloro-2-methoxyphenyl)piperazin-1-yl]propyl}-5-methyl-2,4(1H,3H)-pyrimidinedione hydrochloride, m.p. 194°-195° C.; Anal.: Calcd. for C26H31ClN4O3.(HCl)2 : C, 55.63; H, 6.03; N, 9.98%; Found: C, 55.82; H, 5.94; N, 9.85%;
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05859014 |
| Source dataset | uspto-grants-1999_01 |
| ORD ID | ord-58dcc80374804b8fac3787586d77a41d |
| Source note | uspto-grants-1999_01 |