1-[2-(2,2,2-Trifluoroethoxy)phenyl]piperazine → HCID 70200995, compound

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Reaction Steps

substituting 1-[2-(2,2,2-trifluoroethoxy)phenyl]piperazine and 3-(3-chloropropyl)-1-fur-2-ylmethyl-5-methyl-2,4(1H,3H)-pyrimidinedione gave 3-(3-{4-[2-(2,2,2-trifluoroethoxy)phenyl]piperazine-1-yl}propyl)-1-fur-2-ylmethyl-5-methyl-2,4(1H,3H)-pyrimidinedione hydrochloride, m.p. 132°-134° C.; Anal.: Calcd. for C25H29F3N4O4.(HCl)2 : C, 51.81; H, 5.39; N, 9.66%; Found: C, 51.89; H, 5.44; N, 9.55%;

Provenance & Evidence