1-[2-(2,2,2-Trifluoroethoxy)phenyl]piperazine → HCID 70201952, compound

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Reaction Steps

substituting 1-[2-(2,2,2-trifluoroethoxy)phenyl]piperazine and 3-(3-chloropropyl)-1,5-dimethyl-2,4(1H,3H)-pyrimidinedione gave 3-(3-{4-[2-(2,2,2-trifluoroethoxy)phenyl]piperazin-1-yl}propyl)-1,5-dimethyl-2,4(1H,3H)-pyrimidinedione hydrochloride, m.p. 212°14 213° C.; Anal.: Calcd. for C21H27F3N4O3.(HCl)2 : C, 49.12; H, 5.69; N, 10.91%; Found: C, 48.97; H, 5.68; N, 10.77%;

Provenance & Evidence