HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(3-chloropropyl)-5-methyl-2,4(1H,3H)-pyrimidinedione → 1-{3-[4-(4-chloro-2-methoxyphenyl)piperazin-1-yl]propyl}-5-methyl-2,4(1H,3H)-pyrimidinedione hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(3-chloropropyl)-5-methyl-2,4(1H,3H)-pyrimidinedione | HCID 12091375 | — |
| Reactant | 1-(4-Chloro-2-methoxyphenyl)piperazine | HCID 15840663 | — |
| Product | 1-{3-[4-(4-chloro-2-methoxyphenyl)piperazin-1-yl]propyl}-5-methyl-2,4(1H,3H)-pyrimidinedione hydrochloride | HCID 70201299 | — |
Reaction Steps
substituting 1-(4-chloro-2-methoxyphenyl)piperazine and 1-(3-chloropropyl)-5-methyl-2,4(1H,3H)-pyrimidinedione gave 1-{3-[4-(4-chloro-2-methoxyphenyl)piperazin-1-yl]propyl}-5-methyl-2,4(1H,3H)-pyrimidinedione hydrochloride, m.p. 154°-155° C.; Anal.: Calcd. for C19H25ClN4O3.(HCl)2 : C, 44.05; H, 6.37; N, 10.81%; Found: C, 44.26; H, 6.08; N, 10.46%;
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05859014 |
| Source dataset | uspto-grants-1999_01 |
| ORD ID | ord-72fd971ca9c34fd49b1805a02d7a1f09 |
| Source note | uspto-grants-1999_01 |