反应详情

substituting 1-[4-hydroxy-2-(2,2,2-trifluoroethoxy)phenyl]piperazine and 3-(3-chloropropyl)-5-methyl-2,4(1H,3H)-pyrimidinedione gave 3-(3-{4-[4-hydroxy-2-(2,2,2-trifluoroethoxy)phenyl]piperazin-1-yl}propyl)-5-methyl-2,4(1H,3H)-pyrimidinedione hydrochloride, m.p. 232°-242° C.; Anal.: Calcd. for C20H25F3N4O4.HCl: C, 49.63; H, 5.59; N, 11.02%; Found: C, 49.62; H, 5.65; N, 10.66%;