反应详情

substituting 1-[2-(2,2,2-trifluoroethoxy)pheny]piperazine and 3-(3-chloropropyl)-6-methyl-2,4(1H,3H)-pyrimidinedione gave 3-(3-{4-[2-(2,2,2-trifluoroethoxy)phenyl]piperazin-1-yl}propyl)-6-methyl-2,4(1H,3H)-pyrimidinedione hydrochloride, m.p. 218°-220° C.; Anal.: Calcd. for C20H25F3N4O3.(HCl)2 : C, 48.10; H, 5.44; N, 11.22%; Found: C, 47.85; H, 5.48; N, 11.08%;