HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-[2-(2,2,2-Trifluoroethoxy)phenyl]piperazine → HCID 70202243, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-[2-(2,2,2-Trifluoroethoxy)phenyl]piperazine | HCID 10491565 | — |
| Reactant | HCID 53891804 | HCID 53891804 | — |
| Product | HCID 70202243 | HCID 70202243 | — |
Reaction Steps
substituting 1-[2-(2,2,2-trifluoroethoxy)phenyl]piperazine and 1-(3-chloropropyl)-3-(4-fluorophenyl)-5-methyl-2,4(1H,3H)-pyrimidinedione gave 1-(3-{4-[2-(2,2,2-trifluoroethoxy)phenyl]piperazin-1-yl}propyl)-3-(4-fluorophenyl)-5-methyl-2,4(1H,3H)-pyrimidinedione hydrochloride, m.p. 220°-222° C.; Anal.: Calcd. for C26H28F4N4O3.(HCl)2.(H2O)0.1 : C, 52.46; H, 5.11; N, 9.41%; Found: C, 52.21; H, 4.91; N, 9.26%;
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05859014 |
| Source dataset | uspto-grants-1999_01 |
| ORD ID | ord-aae64c3b0af44a24a67d027611db733c |
| Source note | uspto-grants-1999_01 |