HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Methylbenzyl chloride → HCID 70198305, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Methylbenzyl chloride | HCID 7722 | — |
| Reactant | 5-Methyl-3-[3-[3-[4-[2-(2,2,2-trifluoroethoxy)phenyl]-1-piperazinyl]propyl]-2,4-(1H,3H)-pyrimidinedione] hydrochloride | HCID 3567002 | — |
| Product | HCID 70198305 | HCID 70198305 | — |
Reaction Steps
substituting 3-(3-{4-[2-(2,2,2-trifluoroethoxy)phenyl]piperazin-1-yl}propyl)-5-methyl-2,4(1H,3H)-pyrimidinedione and 4-methylbenzyl chloride gave 3-(3-{4-[2-(2,2,2-trifluoroethoxy)phenyl]piperazin-1-yl}propyl)-1-(4-methylbenzyl)-5-methyl-2,4(1H,3H)-pyrimidinedione hydrochloride, m.p. 141°-143° C.; Anal.: Calcd. for C28H33F3N4O3.(HCl)2 : C, 55.89; H, 5.99; N, 9.12%; Found: C, 56.18; H, 5.99; N, 9.31%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05859014 |
| Source dataset | uspto-grants-1999_01 |
| ORD ID | ord-cae26e3884ae48cdb02367b5f71adcd4 |
| Source note | uspto-grants-1999_01 |