Methyl Methacrylate → HCID 131721074, compound

HRID 342696Notes

Reaction equation

HRID 342696 reaction equation
[CH3:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]([C:10]2[N:14]([CH3:15])[C:13]([CH2:16][C:17]([O-:19])=[O:18])=[CH:12][CH:11]=2)=[O:9])=[CH:6][CH:7]=1.[Na+:20].[CH3:21][C:22]([C:24]([O:26][CH3:27])=[O:25])=[CH2:23]>C(O)C.ClCCl.O>[CH3:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]([C:10]2[N:14]([CH3:15])[C:13]([CH2:16][C:17]([O-:19])=[O:18])=[CH:12][CH:11]=2)=[O:9])=[CH:6][CH:7]=1.[Na+:20].[CH3:23][C:22]([C:24]([O:26][CH3:27])=[O:25])=[CH2:21]

Participants

4

Reactant 2

HCID 6658Methyl MethacrylateHCID 23665411Tolmetin sodium salt

Product 1

HCID 131721074HCID 131721074, compound

Reagents, catalysts & solvents 1

HCID 86647907HCID 86647907, compoundSolvent

Procedure

Separately, 10 g of tolmetin sodium and 10 g of Eudragit L100-55 were dissolved in 500 ml of ethanol/dichloromethane/water mixed liquid (45:45:10) and the solution was spray dried to provide a tolmetin sodium-Eudragit L100-55 complex.

Workup

  1. customdried

Sources & evidence

ORD record
ord-0e431b1d823848c5b007bff3cad121bf
Source dataset
uspto-grants-1999_01
Patent number
US05859048

Reaction notes

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