反应详情

The solution from 2,2-dimethyl-[1,3]dioxolan-4-yl-methyl 2-acetoxybenzoate (5.7 g, 19.4 mmol) in dichloromethane (50 ml) is treated with trifluoroacetic acid (10 ml). After 3 h, the mixture is concentrated in vacuo, the residue is taken up in toluene (30 ml) and the solution is concentrated. The residue is purified by flash chromatography (gradient hexane/ethyl acetate=3/1→2/1 →1/1). Yield: 2.96 g.

1. concentrationthe mixture is concentrated in vacuo
2. concentrationthe solution is concentrated
3. customThe residue is purified by flash chromatography (gradient hexane/ethyl acetate=3/1→2/1 →1/1)