反应详情

The solution from [2S]-1,4-dioxa-spiro[4,5]dec-2-yl-methyl 2-acetoxybenzoate (527 mg, 1.58 mmol) in dichloromethane (10 ml) is treated with trifluoroacetic acid (2 ml). After 2 h at room temperature, the mixture is concentrated, the residue is taken up in toluene (10 ml) and the solution is concentrated. The residue is purified by column chromatography (dichloromethane/methanol=30/1). Yield: 161 mg.

1. concentrationthe mixture is concentrated
2. concentrationthe solution is concentrated
3. customThe residue is purified by column chromatography (dichloromethane/methanol=30/1)