HCID 15334721, compound → {4-[(Methylamino)methyl]phenyl}(phenyl)methanone

HRID 342793Notes

Reaction equation

HRID 342793 reaction equation
[C:1]([N:4]([CH2:6][C:7]1[CH:20]=[CH:19][C:10]([C:11]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)=[O:12])=[CH:9][CH:8]=1)C)(=O)C.Cl.O>>[CH3:1][NH:4][CH2:6][C:7]1[CH:20]=[CH:19][C:10]([C:11]([C:13]2[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=2)=[O:12])=[CH:9][CH:8]=1

Participants

3

Reactant 2

HCID 15334721HCID 15334721, compoundHCID 21885828Hydrate;hydrochloride

Product 1

HCID 15334722{4-[(Methylamino)methyl]phenyl}(phenyl)methanoneYield 86.3%

Procedure

22 g of 4-(N-acetyl-N-methylaminomethyl)benzophenone are refluxed in 100 mL of 1:1 -HCl/water mixture (by volume) for 7 hours. From the reaction mixture there are isolated 16 g of 4-(N-methylaminomethyl)benzophenone. HNMR: δ=1.7 (1H, NH), 2.5 (3H, NCH3), 3.9 (2H, NCH2), 7.1-7.4 (9H, aromatics).

Sources & evidence

ORD record
ord-7ffce052dddc4dcba74dd5192f872af7
Source dataset
uspto-grants-1999_01
Patent number
US05859084

Reaction notes

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