HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzaldehyde → 1,2-Diphenyl-4-methyl-1-penten-3-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzaldehyde | HCID 240 | — |
| Reactant | Water | HCID 962 | — |
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | Benzyl isopropyl ketone | HCID 76163 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | 1,2-Diphenyl-4-methyl-1-penten-3-one | HCID 54502058 | — |
Reaction Steps
A solution of benzaldehyde (6.5g, 0.0617 mole), 3-methyl-1-phenyl-2-butanone (10 g, 0.0617 mole) and piperidine (0.2 g) in benzene (50 ml) was heated to reflux for 20 hours. Water formed during the reaction was removed (azeotrope) by the use of a Dean-Stark trap. The reaction was concentrated to an oil, and the product was purified by silica gel chromatography.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05859257 |
| Source dataset | uspto-grants-1999_01 |
| ORD ID | ord-cd5f20f4fc244376a4ba652a1f500032 |
| Source note | uspto-grants-1999_01 |