Triisopropyl borate → HCID 10569430, compound

HRID 343256Notes

Reaction equation

HRID 343256 reaction equation
FC1C(F)=C(OCCCCCCCC)C=CC=1[B:18]([OH:20])[OH:19].Br[C:22]1[CH:27]=[CH:26][C:25]([C:28]2[CH:33]=[CH:32][C:31]([O:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][CH3:42])=[C:30]([F:43])[CH:29]=2)=[CH:24][CH:23]=1.C([Li])CCC.C(OB(OC(C)C)OC(C)C)(C)C>>[F:43][C:30]1[CH:29]=[C:28]([C:25]2[CH:26]=[CH:27][C:22]([B:18]([OH:20])[OH:19])=[CH:23][CH:24]=2)[CH:33]=[CH:32][C:31]=1[O:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][CH3:42]

Participants

5

Reactant 4

HCID 21531Triisopropyl borateHCID 10714724HCID 10714724, compoundHCID 10850744(2,3-Difluoro-4-(octyloxy)phenyl)boronic acidHCID 178418339Butyllithium

Product 1

HCID 10569430HCID 10569430, compound

Procedure

This was prepared using a similar method to that described for compound 5. Quantities: 4'bromo-3-fluoro-4-octoxybiphenyl (4.95 g, 0.013 mol), n-butyllithium (5 ml, 2.5M/hexane, 0.013 mol), tri-isopropylborate (4.7 g, 0.026 mol).

Workup

  1. customThis was prepared

Sources & evidence

ORD record
ord-cbeac0004f0d45f8b5fcd4b5c937f76e
Source dataset
uspto-grants-1999_01
Patent number
US05861109

Reaction notes

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