Hydrogen Peroxide → 3'-Fluoro-4'-(octyloxy)[1,1'-biphenyl]-4-ol

HRID 343258Notes

Reaction equation

HRID 343258 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([C:17]2[CH:22]=[CH:21][C:20](B(O)O)=[CH:19][CH:18]=2)[CH:5]=[CH:6][C:7]=1[O:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16].[OH:26]O>>[F:1][C:2]1[CH:3]=[C:4]([C:17]2[CH:22]=[CH:21][C:20]([OH:26])=[CH:19][CH:18]=2)[CH:5]=[CH:6][C:7]=1[O:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16]

Participants

3

Reactant 2

HCID 784Hydrogen PeroxideHCID 10569430HCID 10569430, compound

Product 1

HCID 37550353'-Fluoro-4'-(octyloxy)[1,1'-biphenyl]-4-ol

Procedure

This was prepared using a similar method to that described for compound 12. Quantities: 3-fluoro-4-octoxybiphenyl-4'-yl-boronic acid (11) (4.40 g, 0.012 mol), 10% hydrogen peroxide (16 ml, 0.036 mol).

Workup

  1. customThis was prepared

Sources & evidence

ORD record
ord-8c36378b18b4432982e5272644c91008
Source dataset
uspto-grants-1999_01
Patent number
US05861109

Reaction notes

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