Potassium Cyanide → HCID 129667418, compound

HRID 343763Notes

Reaction equation

HRID 343763 reaction equation
[I-].[C-:2]1([CH2:7][N+](C)(C)C)[CH:6]=[CH:5][CH:4]=[CH:3]1.[CH-:12]1[CH:16]=[CH:15][CH:14]=[CH:13]1.[Fe+2:17].[C-:18]#[N:19].[K+]>O>[C-:2]1([CH2:7][C:18]#[N:19])[CH:3]=[CH:4][CH:5]=[CH:6]1.[CH-:12]1[CH:16]=[CH:15][CH:14]=[CH:13]1.[Fe+2:17]

Participants

4

Reactant 2

HCID 9032Potassium CyanideHCID 178483341HCID 178483341, compound

Product 1

HCID 129667418HCID 129667418, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

8.00 g (20.8 mmol) of ferrocenylmethyltrimethylammonium iodide (Strem) and 8 g of KCN (123 mmol) are dissolved in 80 ml of water. The mixture is placed in a round-bottomed flask surmounted by a reflux condenser. The mixture is heated at reflux for 2 hours and is then allowed to cool to room temperature. The product is extracted with 3 times 40 ml of ethyl ether. The organic phase is washed first with 2 times 30 ml of water and then dried over magnesium sulfate. After filtration and evaporation, 4.1 g of ferrocenylacetonitrile are collected.

Workup

  1. customThe mixture is placed in a round-bottomed flask
  2. customsurmounted by a reflux condenser
  3. temperatureThe mixture is heated
  4. temperatureat reflux for 2 hours
  5. extractionThe product is extracted with 3 times 40 ml of ethyl ether
  6. washThe organic phase is washed first with 2 times 30 ml of water
  7. dry with materialdried over magnesium sulfate
  8. filtrationAfter filtration and evaporation, 4.1 g of ferrocenylacetonitrile
  9. customare collected

Sources & evidence

ORD record
ord-ba312351196941c99047c74c0a96818e
Source dataset
uspto-grants-1999_01
Patent number
US05863911

Reaction notes

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