Trifluoroacetic acid → HCID 15069266, compound

HRID 344082Notes

Reaction equation

[CH2:1]([S:4][CH2:5][C:6]1[N:10]([CH2:11][C:12]2[CH:17]=[CH:16][C:15]([C:18]3[C:19]([C:24]([O:26]C(C)(C)C)=[O:25])=[CH:20][CH:21]=[CH:22][CH:23]=3)=[CH:14][CH:13]=2)[C:9]2[CH:31]=[CH:32][CH:33]=[CH:34][C:8]=2[N:7]=1)[CH2:2][CH3:3].FC(F)(F)C(O)=O>>[CH2:1]([S:4][CH2:5][C:6]1[N:10]([CH2:11][C:12]2[CH:17]=[CH:16][C:15]([C:18]3[C:19]([C:24]([OH:26])=[O:25])=[CH:20][CH:21]=[CH:22][CH:23]=3)=[CH:14][CH:13]=2)[C:9]2[CH:31]=[CH:32][CH:33]=[CH:34][C:8]=2[N:7]=1)[CH2:2][CH3:3]

Participants

Reactant 2

HCID 6422Trifluoroacetic acid

HCID 15069124HCID 15069124, compound

Product 1

HCID 15069266HCID 15069266, compound

Procedure

Prepared in analogous manner to Example 9 from tert.butyl 4'-[(2-n-propylthiomethyl-benzimidazol-1-yl)-methyl]biphenyl-2-carboxylate and trifluoroacetic acid.

Sources & evidence

ORD record: ord-41408b5279ea485889c694179eb79291
Source dataset: uspto-grants-1999_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05864043

Reaction notes

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