Trifluoroacetic acid → HCID 67733361, compound

HRID 344148Notes

Reaction equation

[NH2:1][C:2]1[CH:34]=[CH:33][C:5]2[N:6]([CH2:13][C:14]3[CH:19]=[CH:18][C:17]([C:20]4[C:21]([C:26]([O:28]C(C)(C)C)=[O:27])=[CH:22][CH:23]=[CH:24][CH:25]=4)=[CH:16][CH:15]=3)[C:7]([CH2:9][CH2:10][CH2:11][CH3:12])=[N:8][C:4]=2[C:3]=1[NH:35][C:36]([CH3:38])=[O:37].FC(F)(F)C(O)=O>>[NH2:1][C:2]1[CH:34]=[CH:33][C:5]2[N:6]([CH2:13][C:14]3[CH:15]=[CH:16][C:17]([C:20]4[C:21]([C:26]([OH:28])=[O:27])=[CH:22][CH:23]=[CH:24][CH:25]=4)=[CH:18][CH:19]=3)[C:7]([CH2:9][CH2:10][CH2:11][CH3:12])=[N:8][C:4]=2[C:3]=1[NH:35][C:36]([CH3:38])=[O:37]

Participants

Reactant 2

HCID 6422Trifluoroacetic acid

HCID 86749682HCID 86749682, compound

Product 1

HCID 67733361HCID 67733361, compound

Procedure

Prepared in analogous manner to Example 9 from tert.butyl 4'-[(5-aminoacetamino-2-n-butyl-benzimidazol-1-yl)-methyl]biphenyl-2-carboxylate and trifluoroacetic acid.

Sources & evidence

ORD record: ord-9b952261f0b240cb9048cb103e422371
Source dataset: uspto-grants-1999_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05864043

Reaction notes

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