Trifluoroacetic acid → HCID 67573322, compound

HRID 344150Notes

Reaction equation

[NH2:1][C:2]([NH:4][C:5]1[CH:6]=[CH:7][C:8]2[N:12]=[C:11]([CH2:13][CH2:14][CH2:15][CH3:16])[N:10]([CH2:17][C:18]3[CH:23]=[CH:22][C:21]([C:24]4[C:25]([C:30]([O:32]C(C)(C)C)=[O:31])=[CH:26][CH:27]=[CH:28][CH:29]=4)=[CH:20][CH:19]=3)[C:9]=2[CH:37]=1)=[O:3].[F:38][C:39]([F:44])([F:43])[C:40]([OH:42])=[O:41]>>[F:38][C:39]([F:44])([F:43])[C:40]([OH:42])=[O:41].[NH2:1][C:2]([NH:4][C:5]1[CH:6]=[CH:7][C:8]2[N:12]=[C:11]([CH2:13][CH2:14][CH2:15][CH3:16])[N:10]([CH2:17][C:18]3[CH:23]=[CH:22][C:21]([C:24]4[C:25]([C:30]([OH:32])=[O:31])=[CH:26][CH:27]=[CH:28][CH:29]=4)=[CH:20][CH:19]=3)[C:9]=2[CH:37]=1)=[O:3]

Participants

Reactant 2

HCID 6422Trifluoroacetic acid

HCID 15069231HCID 15069231, compound

Product 1

HCID 67573322HCID 67573322, compound

Procedure

Prepared in analogous manner to Example 9 from tert.butyl 4'-[(6-aminocarbonylamino-2-n-butyl-benzimidazol-1-yl)-methyl]biphenyl-2-carboxylate and trifluoroacetic acid.

Sources & evidence

ORD record: ord-cd629a63811c4e66b019581498d15758
Source dataset: uspto-grants-1999_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05864043

Reaction notes

Loading…