Trifluoroacetic acid → HCID 67573039, compound

HRID 344157Notes

Reaction equation

[CH2:1]([NH:4][C:5]([NH:7][C:8]1[CH:9]=[CH:10][C:11]2[N:15]=[C:14]([CH2:16][CH2:17][CH2:18][CH3:19])[N:13]([CH2:20][C:21]3[CH:26]=[CH:25][C:24]([C:27]4[C:28]([C:33]([O:35]C(C)(C)C)=[O:34])=[CH:29][CH:30]=[CH:31][CH:32]=4)=[CH:23][CH:22]=3)[C:12]=2[CH:40]=1)=[O:6])[CH:2]=[CH2:3].[F:41][C:42]([F:47])([F:46])[C:43]([OH:45])=[O:44]>>[F:41][C:42]([F:47])([F:46])[C:43]([OH:45])=[O:44].[CH2:1]([NH:4][C:5]([NH:7][C:8]1[CH:9]=[CH:10][C:11]2[N:15]=[C:14]([CH2:16][CH2:17][CH2:18][CH3:19])[N:13]([CH2:20][C:21]3[CH:22]=[CH:23][C:24]([C:27]4[C:28]([C:33]([OH:35])=[O:34])=[CH:29][CH:30]=[CH:31][CH:32]=4)=[CH:25][CH:26]=3)[C:12]=2[CH:40]=1)=[O:6])[CH:2]=[CH2:3]

Participants

Reactant 2

HCID 6422Trifluoroacetic acid

HCID 67572630HCID 67572630, compound

Product 1

HCID 67573039HCID 67573039, compound

Procedure

Prepared in analogous manner to Example 9 from tert.butyl 4'-[(6-allylaminocarbonylamino-2-n-butyl-benzimidazol-1-yl)-methyl]biphenyl-2carboxylate and trifluoroacetic acid

Sources & evidence

ORD record: ord-5c99cac27af040dba4c6881965de8925
Source dataset: uspto-grants-1999_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05864043

Reaction notes

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