Trifluoroacetic acid → HCID 67733337, compound

HRID 344184Notes

Reaction equation

[CH2:1]([C:5]1[N:9]([CH2:10][C:11]2[CH:16]=[CH:15][C:14]([C:17]3[C:18]([C:23]([O:25]C(C)(C)C)=[O:24])=[CH:19][CH:20]=[CH:21][CH:22]=3)=[CH:13][CH:12]=2)[C:8]2[CH:30]=[C:31]([CH:38]3[CH2:43][CH2:42][CH2:41][CH2:40][CH2:39]3)[CH:32]=[C:33]([NH:34][C:35]([CH3:37])=[O:36])[C:7]=2[N:6]=1)[CH2:2][CH2:3][CH3:4].FC(F)(F)C(O)=O>>[CH2:1]([C:5]1[N:9]([CH2:10][C:11]2[CH:16]=[CH:15][C:14]([C:17]3[C:18]([C:23]([OH:25])=[O:24])=[CH:19][CH:20]=[CH:21][CH:22]=3)=[CH:13][CH:12]=2)[C:8]2[CH:30]=[C:31]([CH:38]3[CH2:39][CH2:40][CH2:41][CH2:42][CH2:43]3)[CH:32]=[C:33]([NH:34][C:35]([CH3:37])=[O:36])[C:7]=2[N:6]=1)[CH2:2][CH2:3][CH3:4]

Participants

Reactant 2

HCID 6422Trifluoroacetic acid

HCID 86749690HCID 86749690, compound

Product 1

HCID 67733337HCID 67733337, compound

Procedure

Prepared in analogous manner to Example 9 from tert.butyl 4'-[(2-n-butyl-6-cyclohexylacetamino-benzimidazol-1-yl)-methyl]biphenyl-2-carboxylate and trifluoroacetic acid.

Sources & evidence

ORD record: ord-44c29f022901480c8a363f6d5224caf5
Source dataset: uspto-grants-1999_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05864043

Reaction notes

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