Trifluoroacetic acid → HCID 54454461, compound

HRID 344216Notes

Reaction equation

[CH2:1]([C:5]1[N:9]([CH2:10][C:11]2[CH:16]=[CH:15][C:14]([C:17]3[C:18]([C:24]([O:26]C(C)(C)C)=[O:25])=[CH:19][CH:20]=[C:21]([Cl:23])[CH:22]=3)=[CH:13][CH:12]=2)[C:8]2[CH:31]=[CH:32][CH:33]=[CH:34][C:7]=2[N:6]=1)[CH2:2][CH2:3][CH3:4].FC(F)(F)C(O)=O>>[CH2:1]([C:5]1[N:9]([CH2:10][C:11]2[CH:12]=[CH:13][C:14]([C:17]3[C:18]([C:24]([OH:26])=[O:25])=[CH:19][CH:20]=[C:21]([Cl:23])[CH:22]=3)=[CH:15][CH:16]=2)[C:8]2[CH:31]=[CH:32][CH:33]=[CH:34][C:7]=2[N:6]=1)[CH2:2][CH2:3][CH3:4]

Participants

Reactant 2

HCID 6422Trifluoroacetic acid

HCID 67572160HCID 67572160, compound

Product 1

HCID 54454461HCID 54454461, compound

Procedure

Prepared in analogous manner to Example 9 from tert.butyl 4'-[(2-n-butyl-benzimidazol-1-yl)-methyl]-5-chloro-biphenyl-2-carboxylate and trifluoroacetic acid.

Sources & evidence

ORD record: ord-49cf014a1cef4d73b95d9ec86b2fd493
Source dataset: uspto-grants-1999_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05864043

Reaction notes

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