HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 4-Methoxy-1-(4-phenylsulfonylbutyl)-4-tert-butoxycarbonylaminomethylpiperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 4-Phenylsulfonylbutyl bromide | HCID 11482789 | — |
| Reactant | tert-butyl N-[(4-methoxypiperidin-4-yl)methyl]carbamate | HCID 54295846 | — |
| Product | 4-Methoxy-1-(4-phenylsulfonylbutyl)-4-tert-butoxycarbonylaminomethylpiperidine | HCID 53834431 | 100.1% |
Reaction Steps
4-Methoxy-4-tert-butoxycarbonylaminomethylpiperidine (1.43 g), 4-phenylsulfonylbutyl bromide (1.7 g) and potassium carbonate (1.6 g) were reacted and treated in the same manner as in Preparation Example 138(1) to give 2.58 g of 4-methoxy-1-(4-phenylsulfonylbutyl)-4-tert-butoxycarbonylaminomethylpiperidine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05864039 |
| Source dataset | uspto-grants-1999_01 |
| ORD ID | ord-ca144ac1fbed449780d06addd04bd017 |
| Source note | uspto-grants-1999_01 |