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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 344310Generated: October 28, 2026

2-Thiophenecarbonyl chloride → HCID 54211601, compound

https://huagongshe.com/reaction/344310

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Thiophenecarbonyl chlorideHCID 78928—
Reactant4-Amino-5-chloro-2-methoxybenzoic acidHCID 81626—
ReactantHCID 53696622HCID 53696622—
ProductHCID 54211601HCID 54211601—

Reaction Steps

3-(3-tert-Butoxycarbonylaminomethylpyrrolidin-1-yl)propylamine (1.05 g) as starting compound was reacted and treated in the same manner as in Example 1 using 2-thiophenecarbonyl chloride (0.48 ml) and 4-amino-5-chloro-2-methoxybenzoic acid (0.82 g) to give 4-amino-5-chloro-2-methoxy-N-(1-(3-(2-thiophenecarbonylamino)propyl)pyrrolidin-3-ylmethyl)benzamide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05864039
Source datasetuspto-grants-1999_01
ORD IDord-7399f61fe4c241488f99a01b1a94d1ab
Source noteuspto-grants-1999_01