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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 344321Generated: October 29, 2026

Methyl Isocyanate → HCID 54480720, compound

https://huagongshe.com/reaction/344321

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl IsocyanateHCID 12228—
Reactant4-Amino-5-chloro-2-methoxybenzoic acidHCID 81626—
ReactantHCID 53808196HCID 53808196—
ProductHCID 54480720HCID 54480720—

Reaction Steps

5-(3-tert-Butoxycarbonylaminomethylpyrrolidin-1-yl)pentylamine (0.84 g) as starting compound was reacted and treated in the same manner as in Example 34 using methyl isocyanate (0.26 ml) and 4-amino-5-chloro-2-methoxybenzoic acid (0.58 g) to give 4-amino-5-chloro-2-methoxy-N-(1-(5-(3-methylureido)pentyl)pyrrolidin-3-ylmethyl)-benzamide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05864039
Source datasetuspto-grants-1999_01
ORD IDord-4e3ffccb41a24f9488e8a39d932a58c5
Source noteuspto-grants-1999_01