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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 344339Generated: October 30, 2026

Phenyl isocyanate → HCID 57091115, compound

https://huagongshe.com/reaction/344339

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenyl isocyanateHCID 7672—
Reactant4-Amino-5-chloro-2-methoxybenzoic acidHCID 81626—
ReactantHCID 53808197HCID 53808197—
ProductHCID 57091115HCID 57091115—

Reaction Steps

5-((3S)-3-tert-Butoxycarbonylaminomethylpyrrolidin-1-yl)-pentylamine (1.52 g) as starting compound was reacted and treated in the same manner as in Example 34 using phenyl isocyanate (0.58 ml) and 4-amino-5-chloro-2-methoxybenzoic acid (0.75 g) to give 4-amino-5-chloro-2-methoxy-N-((3S)-1-(5-(3-phenylureido)pentyl)pyrrolidin-3-ylmethyl)benzamide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05864039
Source datasetuspto-grants-1999_01
ORD IDord-539bea569ba74e8f9752eb75b5168596
Source noteuspto-grants-1999_01