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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 344342Generated: October 31, 2026

Phenyl isocyanate → HCID 22941690, compound

https://huagongshe.com/reaction/344342

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenyl isocyanateHCID 7672—
Reactant4-Amino-5-chloro-2-methoxybenzoic acidHCID 81626—
ReactantHCID 53706156HCID 53706156—
ProductHCID 22941690HCID 22941690—

Reaction Steps

6-((3R)-3-tert-Butoxycarbonylaminomethylpyrrolidin-1-yl)-hexylamine (1.50 g) as starting compound was reacted and treated in the same manner as in Example 34 using phenyl isocyanate (0.57 ml) and 4-amino-5-chloro-2-methoxybenzoic acid (1.01 g) to give 4-amino-5-chloro-2-methoxy-N-((3R)-1-(6-(3-phenylureido)hexyl)pyrrolidin-3-ylmethyl)benzamide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05864039
Source datasetuspto-grants-1999_01
ORD IDord-bce4decd4e964b668d4865c70c8eff86
Source noteuspto-grants-1999_01