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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 344344Generated: November 1, 2026

Methyl isothiocyanate → HCID 53695300, compound

https://huagongshe.com/reaction/344344

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl isothiocyanateHCID 11167—
Reactant4-Amino-5-chloro-2-methoxybenzoic acidHCID 81626—
Reactanttert-Butyl ((1-(2-aminoethyl)pyrrolidin-3-yl)methyl)carbamateHCID 53652257—
ProductHCID 53695300HCID 53695300—

Reaction Steps

2-(3-tert-Butoxycarbonylaminomethylpyrrolidin-1-yl)ethylamine (1 g) as starting compound was reacted and treated in the same manner as in Example 34 using methyl isothiocyanate (0.25 ml) and 4-amino-5-chloro-2-methoxybenzoic acid (0.83 g) to give 4-amino-5-chloro-2-methoxy-N-(1-(2-(3-methylthioureido)ethyl)pyrrolidin-3-ylmethyl)-benzamide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05864039
Source datasetuspto-grants-1999_01
ORD IDord-49e19d9e904946e1bd807275ec56a9aa
Source noteuspto-grants-1999_01