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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 344345Generated: October 31, 2026

Methyl isothiocyanate → HCID 54217784, compound

https://huagongshe.com/reaction/344345

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl isothiocyanateHCID 11167—
Reactant4-Amino-5-chloro-2-methoxybenzoic acidHCID 81626—
ReactantHCID 53696622HCID 53696622—
ProductHCID 54217784HCID 54217784—

Reaction Steps

3-(3-tert-Butoxycarbonylaminomethylpyrrolidin-1-yl)propylamine (1.06 g) as starting compound was reacted and treated in the same manner as in Example 34 using methyl isothiocyanate (0.32 ml) and 4-amino-5-chloro-2-methoxybenzoic acid (0.91 g) to give 4-amino-5-chloro-2-methoxy-N-(1-(3-(3-methylthioureido)propyl)pyrrolidin-3-ylmethyl)benzamide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05864039
Source datasetuspto-grants-1999_01
ORD IDord-281b2ba73a2445218bfb9b16f1f0bd1b
Source noteuspto-grants-1999_01