Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 344347Generated: October 30, 2026

Phenyl Isothiocyanate → HCID 54323585, compound

https://huagongshe.com/reaction/344347

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenyl IsothiocyanateHCID 7673—
Reactant4-Amino-5-chloro-2-methoxybenzoic acidHCID 81626—
Reactanttert-Butyl ((1-(2-aminoethyl)pyrrolidin-3-yl)methyl)carbamateHCID 53652257—
ProductHCID 54323585HCID 54323585—

Reaction Steps

2-(3-tert-Butoxycarbonylaminomethylpyrrolidin-1-yl)ethylamine (1 g) as starting compound was reacted and treated in the same manner as in Example 34 using phenyl isothiocyanate (0.49 ml) and 4-amino-5-chloro-2-methoxybenzoic acid (0.83 g) to give 4-amino-5-chloro-2-methoxy-N-(1-(2-(3-phenylthioureido)ethyl)pyrrolidin-3-ylmethyl)benzamide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05864039
Source datasetuspto-grants-1999_01
ORD IDord-eb6ef075482344f9a8184921de4235af
Source noteuspto-grants-1999_01