3,4-Dichlorobenzaldehyde → 4-amino-5-chloro-N-((1-(6-(3,4-dichlorobenzylamino)hexyl)piperidin-4-yl)methyl)-2-methoxybenzamide

Participants

Role	Name	HCID	Charge
Reactant	3,4-Dichlorobenzaldehyde	HCID 22710	—
Reactant	4-Amino-N-(1-(6-aminohexyl)piperidin-4-ylmethyl)-5-chloro-2-methoxybenzamide	HCID 53683637	—
Product	4-amino-5-chloro-N-((1-(6-(3,4-dichlorobenzylamino)hexyl)piperidin-4-yl)methyl)-2-methoxybenzamide	HCID 53706175	50.7%

Reaction Steps

4-Amino-N-(1-(6-aminohexyl)piperidin-4-ylmethyl)-5-chloro-2-methoxybenzamide (2.0 g) as starting compound and 3,4-dichlorobenzaldehyde (0.97 g) were reacted and treated in the same manner as in Example 121 to give 1.42 g of 4-amino-5-chloro-N-((1-(6-(3,4-dichlorobenzylamino)hexyl)piperidin-4-yl)methyl)-2-methoxybenzamide.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US05864039
Source dataset	uspto-grants-1999_01
ORD ID	ord-30fa7384b34242b9b2340d3f4d1b7bb7
Source note	uspto-grants-1999_01