反应详情

4-Amino-5-chloro-2-methoxy-N-((1-(5-((2-thienylmethyl)amino)-pentyl)piperidin-4-yl)methyl)benzamide (1.5 g) as starting compound, acetaldehyde (0.23 ml) and sodium cyanoborohydride (0.25 g) were reacted and treated in the same manner as in Example 136 to give 0.96 g of 4-amino-5-chloro-N-((1-(5-(N-ethyl-N-(2-thienylmethyl)amino)pentyl)-piperidin-4-yl)methyl)-2-methoxybenzamide.

1. customwere reacted
2. additiontreated in the same manner as in Example 136