反应详情

4-Amino-N-((1-(5-benzylaminopentyl)piperidin-4-yl)methyl)-5-chloro-2-methoxybenzamide (2.0 g) as starting compound, acetone (0.3 ml) and sodium cyanoborohydride (0.35 g) were reacted and treated in the same manner as in Example 136 to give 0.43 g of 4-amino-5-chloro-N-((1-(5-(N-isopropyl-N-benzylamino)pentyl)piperidin-4-yl)methyl)-2-methoxybenzamide.

1. customwere reacted
2. additiontreated in the same manner as in Example 136